{"id":7813,"date":"2024-06-17T08:49:18","date_gmt":"2024-06-17T06:49:18","guid":{"rendered":"https:\/\/www.icotec-medical.com\/?page_id=7813"},"modified":"2024-06-19T12:55:41","modified_gmt":"2024-06-19T10:55:41","slug":"white-paper-3","status":"publish","type":"page","link":"https:\/\/www.icotec-medical.com\/en-us\/clinical-application\/white-papers\/white-paper-3\/","title":{"rendered":"White Paper 3"},"content":{"rendered":"\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/0293US_ClinicalValueBook_2024-04.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Download white paper<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\"><strong><strong>Precision with Care: BlackArmor<sup>\u00ae<\/sup> Carbon\/PEEK Optimizes Radiation Therapy for Improved Outcomes <\/strong><\/strong><br><strong><strong>in Spinal Oncology<\/strong>&nbsp;<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>The field of spinal oncology is at the forefront of a ground-breaking transformation. This white paper explores the compelling benefits of <a href=\"https:\/\/www.icotec-medical.com\/en-us\/clinical-application\/implants\/\">BlackArmor<sup>\u00ae<\/sup> Carbon\/PEEK implants<\/a> in conjunction with postoperative radiation therapy. By examining the current landscape of spinal oncology, the challenges it faces, and the immense potential of <a href=\"https:\/\/www.icotec-medical.com\/en-us\/blackarmor\/\">Carbon\/PEEK technology<\/a>, we aim to shed light on the future of precise, safe, and patient-centric care.<\/p>\n\n\n\n<p>Stereotactic Body Radiation Therapy (SBRT) has emerged as a pivotal tool in the management of spinal oncology cases. SBRT delivers high doses of radiation to small tumor volumes, such as residual tumor cells, reducing the risk of tumor recurrence and improving long-term disease control.<span class=\"modern-footnote\"><sup class=\"modern-footnotes-footnote modern-footnotes-footnote--expands-on-desktop \" data-mfn=\"1\" data-mfn-post-scope=\"0000000062fbf9c00000000009ef4fc4_7813\"><a href=\"javascript:void(0)\"  role=\"button\" aria-pressed=\"false\" aria-describedby=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\">1<\/a><\/sup><span id=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\" role=\"tooltip\" class=\"modern-footnotes-footnote__note\" tabindex=\"0\" data-mfn=\"1\">Cao, Y., et al., The impact of local control on widespread progression and survival in oligometastasis-directed SBRT: results from a large international database. Radiother Oncol, 2023: p. 109769.<\/span><\/span><\/p>\n\n\n\n<p>A randomized international phase II study has demonstrated a 22-month improvement in median overall survival (OS) with SBRT for oligometastatic cancer patients compared to patients who received a standard care such as conventional External Beam Radiation Therapy (cEBRT), with a 25% survival benefit at 5 years.<span class=\"modern-footnote\"><sup class=\"modern-footnotes-footnote modern-footnotes-footnote--expands-on-desktop \" data-mfn=\"2\" data-mfn-post-scope=\"0000000062fbf9c00000000009ef4fc4_7813\"><a href=\"javascript:void(0)\"  role=\"button\" aria-pressed=\"false\" aria-describedby=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\">2<\/a><\/sup><span id=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\" role=\"tooltip\" class=\"modern-footnotes-footnote__note\" tabindex=\"0\" data-mfn=\"2\">Palma, D.A., et al., Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligometastatic Cancers: Long-Term Results of the SABR-COMET Phase II Randomized Trial. J Clin Oncol, 2020. <strong>38<\/strong>(25): p. 2830-2838.\u202f<\/span><\/span><\/p>\n<\/div>\n<\/div>\n\n\n<div id=\"quotes\" class=\"large\">\n\n      <div class=\"quote \">\n      <div class=\"container\">\n        \n                \n                \n          <figure style=\"background-image:url(https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Braunstein-Steve-e1710232543435.jpg);\"><\/figure>\n        \n                \n        <div class=\"text\">\n          \n          <blockquote>\n            \u201cHaving the confidence of delivering the prescribed dose allows us to minimize the safety margins and plan higher dose to the tumor.\u201d          <\/blockquote>\n          <div class=\"author\">\n            <div class=\"name\">Dr. Steve Braunstein<\/div>\n            <div class=\"position\">Radiation Oncologist<\/div>\n          <\/div>\n          \n        <\/div>\n        \n              \n      <\/div>\n    <\/div>\n    \n<\/div>\n\n<script>\n\n  jQuery(document).ready( function($){\n  \n    $(\"#quotes\").slick({\n      slidesToShow: 1,\n      slidesToScroll: 1,\n      fade: true,\n      loop: true,\n      infinite: false,\n      arrows: true,\n      adaptiveHeight: true,\n      dots: false,\n      autoplay: false,\n      autoplaySpeed: 4000,\n    });\n    \n  });\n\n<\/script>\n\n\n\n<div class=\"wp-block-getwid-section\"><div class=\"wp-block-getwid-section__wrapper\"><div class=\"wp-block-getwid-section__inner-wrapper\"><div class=\"wp-block-getwid-section__background-holder\"><div class=\"wp-block-getwid-section__background\"><\/div><div class=\"wp-block-getwid-section__foreground\"><\/div><\/div><div class=\"wp-block-getwid-section__content\"><div class=\"wp-block-getwid-section__inner-content\">\n<div class=\"wp-block-getwid-accordion has-icon-left\" data-active-element=\"none\">\n<div class=\"wp-block-getwid-accordion__header-wrapper\"><span class=\"wp-block-getwid-accordion__header\"><a href=\"#\"><span class=\"wp-block-getwid-accordion__header-title\">Addressing the Challenges of Metal Implants in Spinal Tumor Radiation Therapy<\/span><span class=\"wp-block-getwid-accordion__icon is-active\"><i class=\"fas fa-plus\"><\/i><\/span><span class=\"wp-block-getwid-accordion__icon is-passive\"><i class=\"fas fa-minus\"><\/i><\/span><\/a><\/span><\/div><div class=\"wp-block-getwid-accordion__content-wrapper\"><div class=\"wp-block-getwid-accordion__content\">\n<p>Often used metal implants, such as titanium, interfere with imaging and radiation beams, thus limiting the administration of radiation therapy across multiple steps.&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p>The artifacts created by metal implants obscure critical areas such as the spinal cord and epidural space and lead to uncertainties in radiation planning and administration.<span class=\"modern-footnote\"><sup class=\"modern-footnotes-footnote modern-footnotes-footnote--expands-on-desktop \" data-mfn=\"3\" data-mfn-post-scope=\"0000000062fbf9c00000000009ef4fc4_7813\"><a href=\"javascript:void(0)\"  role=\"button\" aria-pressed=\"false\" aria-describedby=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\">3<\/a><\/sup><span id=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\" role=\"tooltip\" class=\"modern-footnotes-footnote__note\" tabindex=\"0\" data-mfn=\"3\">Muller, B.S., et al., The dosimetric impact of stabilizing spinal implants in radiotherapy treatment planning with protons and photons: standard titanium alloy vs. <a href=\"https:\/\/www.icotec-medical.com\/en-us\/blackarmor\/\">radiolucent carbon-fiber-reinforced PEEK<\/a> systems. J Appl Clin Med Phys, 2020.\u202f<\/span><\/span><\/p>\n\n\n\n<p>Challenges in delineating the tumor volume and organs at risk are compounded by uncertainties in dose calculations resulting from erroneous information caused by imaging artifacts. The dose coverage region in the epidural space, between the spinal cord and the vertebral body, is at high risk of tumor recurrence after treatment, even without instrumentation.<span class=\"modern-footnote\"><sup class=\"modern-footnotes-footnote modern-footnotes-footnote--expands-on-desktop \" data-mfn=\"4\" data-mfn-post-scope=\"0000000062fbf9c00000000009ef4fc4_7813\"><a href=\"javascript:void(0)\"  role=\"button\" aria-pressed=\"false\" aria-describedby=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\">4<\/a><\/sup><span id=\"mfn-content-0000000062fbf9c00000000009ef4fc4_7813\" role=\"tooltip\" class=\"modern-footnotes-footnote__note\" tabindex=\"0\" data-mfn=\"4\">Chan, M.W., et al., Patterns of epidural progression following postoperative spine stereotactic body radiotherapy: implications for clinical target volume delineation. J Neurosurg Spine, 2016. <strong>24<\/strong>(4): p. 652-9.<\/span><\/span><\/p>\n\n\n\n<p>The uncertainties associated with metal hardware lead to larger safety margins around the spinal cord and target volume.&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"474\" src=\"https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-1024x474.jpg\" alt=\"T2-weighted MRI showing the radiation plans for a patient with CFRP (A) and titanium (B) (1)\" class=\"wp-image-7832\" srcset=\"https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-1024x474.jpg 1024w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-300x139.jpg 300w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-768x355.jpg 768w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-1536x711.jpg 1536w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-2048x948.jpg 2048w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-1568x726.jpg 1568w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/T2-weighted-MRI-showing-the-radiation-plans-for-a-patient-with-CFRP-A-and-titanium-B-1-1320x611.jpg 1320w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Axial MRIs showing the radiation plans for a patient with Carbon\/PEEK (A) and titanium (B) screws, respectively.<br>Structure identification on postoperative MRI is facilitated by reduced artifacts with BlackArmor<sup>\u00ae<\/sup> Carbon\/PEEK.<br>Taken from Almeida et al., 2023.<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-getwid-accordion__header-wrapper\"><span class=\"wp-block-getwid-accordion__header\"><a href=\"#\"><span class=\"wp-block-getwid-accordion__header-title\">Beyond the Blur: Artifact-Free MR Imaging with BlackArmor<sup>\u00ae<\/sup> Carbon\/PEEK for Improved Spinal Metastasis Monitoring<\/span><span class=\"wp-block-getwid-accordion__icon is-active\"><i class=\"fas fa-plus\"><\/i><\/span><span class=\"wp-block-getwid-accordion__icon is-passive\"><i class=\"fas fa-minus\"><\/i><\/span><\/a><\/span><\/div><div class=\"wp-block-getwid-accordion__content-wrapper\"><div class=\"wp-block-getwid-accordion__content\">\n<p><a href=\"https:\/\/www.icotec-medical.com\/en-us\/clinical-application\/implants\/\">Radiolucent implants<\/a> significantly improve imaging quality, enabling radiation oncologists to achieve a more precise delineation of the spinal cord, critical organs at risk, and the tumor volume. This precise delineation is crucial as it allows for the delivery of the maximum safe dose to the tumor, enhancing the likelihood of successful treatment, while minimizing the risk of toxicity to surrounding organs at risk. Such advancements in visualization and tumor delineation are especially beneficial in treating patients with complex tumors or those with radioresistant histology, as it enables dose-escalated treatments. These treatments aim to increase the probability of long-term local control of the tumor, thus potentially improving patient outcomes. \u202f&nbsp;<\/p>\n\n\n\n<p>For physicians, the integration of <a href=\"https:\/\/www.icotec-medical.com\/en-us\/clinical-application\/implants\/\">BlackArmor<sup>\u00ae<\/sup> Carbon\/PEEK implants<\/a> in the management of spinal oncology marks a paradigm shift in treatment, promising enhanced therapeutic precision and superior patient-centric care.<\/p>\n\n\n\n<figure class=\"wp-block-image alignright size-large is-resized\"><img decoding=\"async\" width=\"1024\" height=\"765\" src=\"https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology-1024x765.png\" alt=\"Radiooncology\" class=\"wp-image-7823\" style=\"width:512px;height:383px\" srcset=\"https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology-1024x765.png 1024w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology-300x224.png 300w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology-768x574.png 768w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology-1536x1147.png 1536w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology-1568x1171.png 1568w, https:\/\/www.icotec-medical.com\/wp-content\/uploads\/2024\/06\/Radiooncology.png 2000w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"has-text-align-center has-small-font-size\">NOTE: Not all icotec implants have been evaluated for safety in the MR environment. <br>Some have not been tested for heating or unwanted movement in the MR environment. <br>The safety of these implants in the MR environment is unknown. Performing an&nbsp;MR exam on <br>a person who has such a medical device may result in injury. Please consult the respective instructions for use&nbsp;regarding information on the safety and compatibility of the individual icotec implants in the MR environment.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.icotec-medical.com\/en-us\/clinical-application\/white-papers\/\">Back to overview<\/a><\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Precision with Care: BlackArmor\u00ae Carbon\/PEEK Optimizes Radiation Therapy for Improved Outcomes in Spinal Oncology&nbsp; The field of spinal oncology is at the forefront of a ground-breaking transformation. This white paper explores the compelling benefits of BlackArmor\u00ae Carbon\/PEEK implants in conjunction with postoperative radiation therapy. By examining the current landscape of spinal oncology, the challenges it [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":7810,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"inline_featured_image":false,"footnotes":""},"class_list":["post-7813","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>BlackArmor\u00ae Carbon\/PEEK Optimizes Radiation Therapy for Improved Outcomes in Spinal Oncology\u00a0 | icotec<\/title>\n<meta name=\"description\" content=\"This white paper concisely highlights the importance of improved postoperative SBRT for patients with spinal metastases.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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